Statistical Genetics and Bioinformatics in Paris, FR
Open position at Institut Pasteur (Paris, France)
In the framework of the LabEx consortium « Milieu Intérieur » (MI), *a
position in statistical genetics and bioinformatics is open from March
2014* at the Institut Pasteur in Paris. The goal of the MI consortium is
to define the naturally-occurring variation of the human immune
responses to an unprecedented scale. Thousands of aspects of the
variation of the immune response (i.e., gene expression, protein
variation, cellular phenotypes, etc.) to pathogens and immune stimuli
are being defined in a large cohort of 1000 healthy individuals. The
integration of these datasets with the degree of genome-wide variation
of the human genome, variation in microbiota, and a number of
demographic variables will allow us to evaluate the respective impact of
genetic, environmental and sociocultural factors on the inter-individual
variability of the immune response, which in turn can account for
differences in susceptibility to infectious disease, and response to
therapeutic treatment and vaccines.
The candidate will be responsible for data analyses in the context of
this project and will work in a multidisciplinary team that integrates
human genetics, population genetics, immunology, evolutionary biology
and systems biology. This ambitious project needs cutting-edge and
innovative methods for the statistical analyses of the data. We look for
a candidate with strong experience in large-scale data analyses (data
mining), and advanced tools in statistical inference (e.g., linear and
generalised linear models, Bayesian statistics, MCMC algorithms, etc.).
We expect the candidate to have a strong interest in the development of
new statistical approaches. Knowledge of genomics and biology is not
necessary but will be appreciated.
*Requirements:*The applicant should have a PhD, or equivalent degree, in
Biostatistics, Bioinformatics or Statistical Genetics, or several years
of experience in these fields. Team spirit and dynamism are essential.
Salary will depend on previous experience.
*Contact*: To apply, send your CV and a letter describing your research
interests and skills (in a single pdf file) to Dr Lluis Quintana-Murci,
Unit of Human Evolutionary Genetics, Institut Pasteur, by e-mail:
quintana@pasteur.fr