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Postdoctoral position: Co-evolution among Soybean and its Pathogens and Pests

Ohio State University is seeking a postdoctoral researcher to join an interdisciplinary project studying various co-evolutionary aspects of soybean and its pests and pathogens, including genetic, metabolomic, biochemical and function interactions.  The research efforts are focused on identifying the causal genes that contribute to expression of resistance to many of the pests (pathogens and insects), and retain or improve yield and soybean quality. In the long-term, understanding these foundational and basic interactions in an evolutionary framework will lead to enhanced crop production.

Applicants should have an interest and experience in plant-pest/pathogen co-evolutionary interactions using a range of techniques from quantitative and molecular genetics, genomics, metabolomics, transcriptomics, network analysis, and/or bioinformatics.  Skills related to genome assembly and annotation, RNA-Sequencing, functional analysis of candidate genes, metabolomic pathway development or other molecular biology techniques are a plus.

The position is purely interdisciplinary, collaborating with faculty in Horticulture and Crop Science, Plant Pathology and Entomology.  This position is a full-time, term appointment for an initial period of one year, and can be extended based on funding and performance.  Travel between the Wooster (Ohio Agricultural Research and Development Center) and Columbus campuses of Ohio State will be needed.

This postdoctoral position will be a member of the Center for Applied Plant Sciences (CAPS; https://caps.osu.edu/. For specific information about the research and opportunity, contact Anne Dorrance (dorrance.1@osu.edu), Chris Taylor (taylor.1886@osu.edu), Andrew Michel (michel.70@osu.edu), or Leah McHale (mchale.21@osu.edu).

Interested applicants should send 1) a letter of interest, 2) a single PDF document containing the applicant’s CV and contact information for three professional references, 3) reprint(s) of relevant authored publications to dorrance.1@osu.edu.  Review of applications will begin on March 31, 2013 and continue until a satisfactory candidate is found.

Junior Research Group Leader in Functional Genetics and Genomics of Fungi

The Senckenberg Society has an internationally known for all fields of Natural History research is seeking a Junior Research Group Leader in Functional Genetics and Genomics of Fungi. This position will exist in the larger framework of a government funded LOEWE excellence cluster in Integrative Fungal Research (IPF)  in Frankfurt am Main. The Senckenberg Society runs six research institutes and two museums in Germany and is also custodian of the UNESCO World Heritage Site at Messel.

Senckenberg is looking for an individual whose research will be adding significantly to the research aims of the LOEWE excellence cluster “Integrative Fungal Research”. The cluster includes researchers in mycology from Goethe-University Frankfurt a.M., Justus-Liebig-University Gießen, Philipps-University Marburg, University Kassel, and the Senckenberg Society.

The aim of the LOEWE excellence cluster will be to synergistically tie together the basic research areas of biodiversity research, molecular genetics, and genomics with translational research in biochemistry and biotechnology. Thus, the research cluster offers an ideal environment for scientific development and profiling.

Salary and benefits are according to a public service position in Germany (TV-H E14).  The position is limited to three years, with the possibility of extension for two years in case of positive evaluation. Senckenberg advocates gender equality. Women and other underrepresented groups are therefore strongly encouraged to apply. The possibility of academic development (habilitation, equivalent to assistant/associate professor) will be given.

Apart from the salary of the group leader, a competitive core funding for instrumentation, running costs and personnel will be provided.

Research expertise in the areas of comparative genomics and transcriptomics, annotation of metabolic pathways and regulatory networks, or systems biology of fungi or oomycetes are particularly welcome. Applicants should have an international track record and have demonstrated their ability to develop innovative ideas in their field of
research. Previous experience with independent research is a plus but not mandatory. A record in third party funding acquisition is an advantage; willingness to acquire funding through research proposals is required.

To apply, applicants are encouraged to submit a cover letter, C.V., statement of research achievements, future research proposal (only one page, each), certificates (PhD, MSc, BSc, or similar) and the names of three scientists who could provide references. Applications should be submitted in a single PDF file by
e-Mail to recruiting@senckenberg.de.

Inquiries about the LOEWE excellence cluster Integrative Fungal Research and regarding the position can be made by contacting directly Prof. Dr. Marco Thines (thines@bio.uni-frankfurt.de).

The reference number is: #01-13001. Closing date: January 31, 2013.

Engineer in Bio-Computing position available at the Institute of Genomics – France

Environment:

The LABGeM team located at the Institute of Genomics of the French Atomic Energy Commission (CEA- Genoscope, Evry – FRANCE) is essentially composed of bio-IT specialists. The current fields of research revolve around two main scopes, namely expert  annotation of procaryotic genomes and comparative genomics of prokaryotes in the broadest sense of the term. Due to its recognized expertise in the world of bacterial genomics, our laboratory establishes numerous collaborations especially within the framework of ANR calls (The French National Research Agency).  To complete successfully one of our projects (ANR ReplicolScope), we are currently seeking for an engineer in bio-computing.

Project scope:

Constant increase in acquired resistance to antibiotics is a major problem of public health. In the case of Escherichia coli species, one of the ubiquitous opportunistic pathogen of Man and Animals, we are currently facing the emergence of Extended Spectrum Beta-lactamases (ESBL) capable of hydrolyzing all Beta-lactams but carbapenems and cephamycins. The goal of the *ReplicolScope* project  is to better understand the interactions between plasmids harboring ESBL genes and various populations of E. coli in order to explain the evolutionary success of ESBL.

Missions:

The successful candidate will participate in *missions* assigned to the laboratory within the framework of the *Replicolscope* project:   1.  setting up of a relational database containing sequences and other MetaData related to plasmids of Enterobacteria (public and locally sequenced), 2. performing syntactic and functional annotations of plasmidic sequences based on original strategies for the construction of gene models and on the protein families characterization.  3.   integrating and performing comparative analyses of the data in order to target genomic regions for which expert annotation is required. 4.  training of the partners of the project on the use of the platform MicroScope / ReplicoScope. The whole work will rely on the use and the extension of the MicroScope platform developed in our laboratory (further details at http://www.genoscope.cns.fr/agc/microscope).

Required skills and experiences:

The successful applicant will have: a Master degree in computer science, computational biology, or related field , a good knowledge of Prokaryote genomics,  experience in tools devoted to genome analyses (comparative genomics, statistics), experience in oriented bioinformatics programming languages in UNIX environment (Bash, Perl, SQL, Java) and compiled languages (C/C++), relational databases and construction of computational pipelines.

Position:

Minimum one year fixed-term contract. Effective start date ASAP. Salary will depend on the candidate’s experience (minimum gross salary: 2200 euros/month).

Closing Date: *April 11 2012*.  Send detailed CV and a cover letter along with names of 3 references to Claudine Médigue and Stéphane Cruveiller (cmedigue@genoscope.cns.fr) & Stéphane Cruveiller (scruveil@genoscope.cns.fr).