Position in large transcriptome and genome resequencing
A bioinformatics position is available in the group of Jochen Wolf at
the Evolutionary Biology Centre in Uppsala, Sweden. The position is
initially limited to 2-years and after evaluation can be made permanent.
Background.
We are a young, growing research group that applies an integrative
approach to study evolutionary processes in natural populations. Major
research themes include speciation and genome evolution. One of the
main question is to understand the evolutionary processes and genetic
mechanisms underlying species divergence (e.g. Ellegren et al. 2012,
Shafer et al. 2013, Poelstra et al. in press). Using large-scale
genetic approaches, as well as field based experiments, we characterize
genomic divergence across populations and (sub-)species and assess its
relationship to functional phenotypic divergence. In addition, we engage
in (macro-evolutionary) comparative approaches to study evolution across
larger timescales (e.g. Nabholz et al. 2013) and sometimes get interested
in methodology (Mugal et al. 2014, Vijay et al. 2013). Empirical
systems currently include birds (swallows and corvids), marine mammals
(pinnipeds and killer whales) and the European hemiclonal Pelophylax
water frog system.
The position.
The successful applicant will be responsible for management of large
transcriptome and genome resequencing data sets and engage actively
in ongoing research projects. The applicant is familiar with genetic
databases and has experience in standard bioinformatic approaches using
high throughput sequencing data from Illumina, SOLID, IonTorrent and
(increasingly) single molecule sequencing. Common tasks involve data
management, genome assembly and annotation of vertebrates (Birds ca. 1.2
Gb, marine mammals: ca. 3Gb), multiple sequence alignments, mapping,
genotyping, etc. Proficiency in relevant programming languages (UNIX,
Perl, Python, etc.) is naturally assumed. A background in population
genomics or comparative genomics is beneficial.
The environment.
The Evolutionary Biology Centre (http://www.ebc.uu.se/) is one of the
world’s leading research institutions in evolutionary biology. It is
part of Uppsala University which has been ranked first place among all
European Universities in the subject of biology (CHE European ranking)
and bridges a broad variety of disciplines. The scientific environment
with numerous seminars, journal clubs and social activities offer
excellent possibilities for contacts and collaborations. A graduate school
currently directed by Jochen Wolf provides a framework for courses and
high-profile seminars broadly reflecting the group’s research interests
(http://www.ebc.uu.se/education/postgrad/gradschool/Seminars). Our
lab is part of the Department of Evolutionary Biology
(http://www.ebc.uu.se/Research/IEG/evbiol/), an active
environment addressing fundamental evolutionary questions
with a wide range of different approaches. As a member of
the Science for Life Laboratory (http://www.scilifelab.se/)
we make extensive use of high performance computing resources
(https://www.uppmax.uu.se/uppnex) and extended bioinformatic
infrastructure (http://www.scilifelab.se/platforms/bioinformatics/). We
also actively interact with research groups of the nearby BioMedicalCentre
(http://www.imbim.uu.se/Research). The lab is situated in the student
town of Uppsala, that offers rich opportunities in cultural and outdoor
activities. Sweden’s capital Stockholm is less than an hour’s train
ride away.
How to apply.
Applicants with a suitable background with and without
a PhD degree are encouraged to apply. Applications
including a CV, a statement of motivation and the contact
details of at least two references should be sent to:
http://www2.personalavd.uu.se/jobb/appform.php?lang=en&case=UFV-PA%202014/1596
The positions remains open until filled. Starting date is
flexible. For more information contact jochen.wolf@ebc.uu.se or see
http://www.ebc.uu.se/Research/IEG/evbiol/research/Wolf/.