A postdoctoral position is available immediately at the Computational
Genomics and Bioinformatics Group in the Department of Computer Engineering
in Bilkent University, Ankara, Turkey. The position is joint with the Somel
Lab of the Department of Biological Sciences in Middle East Technical
University.
As the Computational Genomics and Bioinformatics Group, we develop
combinatorial algorithms to analyze genomic sequence data to discover,
genotype, and phase genomic variants with a special focus on structural
variation and segmental duplication. We are also interested in de novo
genome assembly and transcriptome analysis. We apply our algorithms on
sequence data generated from the genomes of various organisms including
humans, to catalog normal variation, and study genome evolution.
The successful candidate will be responsible for leading a project that
involves de novo assembly and further analysis of the genome of pearl
mullet (Chalcalburnus tarichi). The pearl mullet is the only fish (and the
only vertebrate) that lives in Lake Van in eastern Turkey, and it shows
remarkable adaptation to the saline and extremely alkaline (pH 9.8) lake
water. The genetic and physiological mechanisms underlying this unique
trait, as well as the pearl mullet’s population structure, remain unknown.
The project will include the following steps:
• De novo assembly and the annotation of the pearl mullet genome using
both Illumina and Pacific Biosciences data.
• Comparative genomics analysis to understand the evolution of the
Cyprinidae family and adaptive evolution of the pearl mullet.
• Transcriptome analysis for genome annotation; identification of gene
expression networks underlying adaptation to alkaline water.
• Population genomics analysis of samples from different sections of the
lake to understand the pearl mullet’s migration and breeding patterns and
population history.
More details can be found in our lab web page at:
http://donut.cs.bilkent.edu.tr
Requirements:
• Ph.D. degree in bioinformatics, genomics, computer science, or related
fields. Ph.D. candidates who expect to graduate soon are welcome to apply.
• Experience in genome assembly and annotation is strongly preferred.
• Experience in evolutionary genetics, population genomics, or
transcriptome analysis is a plus.
• Strong programming skills in at least one high level programming
language; such as C, C++, Java, or Python.
A competitive salary and subsidized on-campus accommodation will be
provided. The successful candidate will also be encouraged to apply for the
TÜBİTAK 2232 (for Turkish candidates) and the Co-Funded Brain Circulation
Scheme fellowship programs (all candidates; gross monthly salary €4,167;
deadline September 19, 2014; URL: http://www.cocirc.tubitak.gov.tr/node/9).
The initial appointment will be for one year, with renewal available for
two more years.
Applicants should email a cover letter, CV, brief research statement and
list of 3 references to Dr. Can Alkan (calkan@cs.bilkent.edu.tr), or Dr.
Mehmet Somel (somel.mehmet@gmail.com). Please combine all files into a
single PDF and use the subject line “Postdoc Application (Pearl Mullet):
(name)”.