Huang, Hanwen
Research Interest:
Statistical machine learning and data mining, biostatistics and bioinformatics, statistical genetics, high-dimensional data analysis, statistical computation and Bayesian statistics.
Research Interest:
Statistical machine learning and data mining, biostatistics and bioinformatics, statistical genetics, high-dimensional data analysis, statistical computation and Bayesian statistics.
Research Interest
Micro-electro-mechanical systems, microfluidics, and nanotechnology
Research Interest
Micro-electro-mechanical systems, microfluidics, and nanotechnology
Research Interests
Microbiology, medical mycology, and physiology and genetics of fungi
Research Interest
The primary focus of our research lab is the organization of grass genomes, particularly wheat, millets, and a biofuel crop known as switchgrass. We employ genetic and genomic analyses of the species themselves as well as comparative analyses of crop and sequenced model genomes to go about this. Research is funded by the National Science Foundation (NSF), United States Department of Agriculture (USDA), and Department of Energy.
Research Interest
Research in our lab is broken down into four fields: systems biology for biofuel study, cancer bioinformatics, comparative genomics, and structural bioinformatics. We are interested in developing computational tools for solving biological problems. Particular areas of work include cancer computation and systems biology, plant cell-wall synthesis genes and pathways, microbial genome structure, pathway and network inference, and protein structure prediction.
Research Interest
Much of the research in our lab has been sparked by the simple question, what makes a tree a tree? Some of the areas we are interested in include plant biology, tree longevity, gene functionalities, proteins, metabolites, gene family evolution, functional diversification, transgenic manipulation, transcriptomics, and bioinformatics.
We use a variety of experimental approaches ranging from transcriptomics (microarray and RNA-Seq) to metabolite profiling (GC-MS and HPLC-MS) and bioinformatics to the more traditional tools of genetics, biochemistry, plant physiology and transgenics to further our knowledge on these topics.
Research Interest
The research in our lab focuses on the immunology and pathogenesis of Trypanosoma cruzi infection and the resulting disease syndrome known as Chagas disease. Currently, there are no vaccines for prevention of T. cruzi infection and current chemotherapeutic regimens have had limited success. We are interested in answering three questions to learn more about the immunology and pathogenesis of T. cruzi:
1. How is immune control initiated and maintained during the infection?
2. How does T. cruzi manage to avoid immune clearance and maintain an infection for decades in hosts?
3. What is the relationship between immunity, parasite persistence, and disease development?